Sheldon’s cross-country train trip will take him on quite an adventure when The Big Bang Theory returns.

CBS released the first photos from the upcoming season premiere, which feature Sheldon having a grand old time in various places, including Chicago, before seemingly falling victim to thievery in Arizona.

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Image Credit: CBS

How bad does his trip get? Well, he ends up in his underwear.

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Image Credit: CBS

Fortunately, Amy and Leonard make the trek to Arizona to pick him up.

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Image Credit: CBS

Elsewhere, Penny interviews for a job at Bernadette’s pharmaceutical company, headed up by guest-star Stephen Root. (Have you seen his stapler?)

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Image Credit: CBS

Of course, it’s not long before Sheldon is back in his spot in the safety of Pasadena.

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Image Credit: CBS

The Big Bang Theory returns Sept. 22 at 8 p.m. on CBS.

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