Ladies, gird your heart. It’s the 25th anniversary of perhaps the most aw-inducing comedy of all time, “Three Men and a Baby” (which was released on November 25, 1987).

The Leonard Nimoy-directed (yes, really) film followed three playboy pals (Ted Danson, Tom Selleck and Steve Guttenberg) whose lives are turned upside down when a cooing bundle is dropped off at their doorstep. Suddenly, they’re overrun with bottles instead of brews and lullabies instead of ladies.

The comedy was the highest grossing film of 1987, even surpassing the hugely popular “Fatal Attraction.” Although the trio reunited three years later for “Three Men and a Little Lady,” the film earned mostly negative reviews.

In honor of baby Mary’s 25th birthday (Congrats! You can now rent a car!) let’s take a look at what’s become of the cast of “Three Men and a Baby.” (Side note: Unfortunately, Lisa and Michelle Blair, the twins who portrayed Mary Bennington, the baby in the film, haven’t been seen on screen since the the movie’s release, and little is known about their personal lives today.)

PHOTOS:

  • Tom Selleck (Peter Mitchell)

  • Tom Selleck (Peter Mitchell)

    The mustachioed Tom Selleck took a break from his popular television serious “Magnum, P.I.” to star in 1987’s “Three Men and a Baby.” Here, he took on the role of architect Peter Mitchell, part of a trio of playboy besties living in a posh Manhattan loft. While Selleck continued to star in movies after the film, his most famous roles would come from his TV appearances. In the late ’90s, he garnered fame as Dr. Richard Burke, Courtney Cox’s love interest on “Friends.” Since 2010, Selleck has played NYPD Police Commissioner Frank Reagan in the CBS drama “Blue Bloods.” And yes, he still has that patented mustache.

  • Ted Danson (Jack Holden)

  • Ted Danson (Jack Holden)

    Like Selleck, Ted Danson had made a name for himself in the television world before going on to star in the comedy flick. From 1982-1993, he starred as Sam Malone in the hit series “Cheers.” In “Three Men,” Danson played the love-em-and-leave-em actor Jack Holden, whose life takes on a more serious tone when he discovers he is a new father. While he would continue to make film appearances after “Baby,” the majority of his work would come from TV. He starred as the curmudgeon physician Dr. John Becker in “Becker” and earned popularity playing himself in Larry David’s “Curb Your Enthusiasm.” Danson has been nominated for 15 Emmy Awards during his 30-year career, taking the gold home twice. Most recently, the actor has been appearing on the CBS drama “CSI: Crime Scene Investigation.”

  • Steve Guttenberg (Michael Kellam)

  • Steve Guttenberg (Michael Kellam)

    While Steve Guttenberg may now be the lesser-known of his co-stars, Guttenberg had a lively film career behind him at the time of the film’s release. He first garnered attention after appearing in 1982’s conversation-heavy “Diner and went on to star in the film franchise “Police Academy.” After “Three Men and a Baby,” Guttenberg starred alongside Mary-Kate and Ashley Olsen in “It Takes Two.” Today, Guttenberg is active in the charity world, having founded Guttenhouse an apartment complex for foster children. In 2008, Guttenberg was honored with the Tony Randall Lifetime Achievement Award for his acting career and his community service efforts.

  • Nancy Travis (Sylvia Bennington)

  • Nancy Travis (Sylvia Bennington)

    In her third role ever, Nancy Travis was cast as the female foil Sylvia Bennington in “Three Men.” After her performance, she went on to star in many 90’s favorites like “Internal Affairs” and “So I Married an Axe Murderer.” Travis and co-star Danson would eventually reunite on the set of his show “Becker.” From 2007 to 2009, she played the female lead, replacing Terry Farrell. In 2011, Travis appeared in the sitcom “Last Man Standing” opposite Tim Allen, but her role was short-lived and her character was written out after the first two episodes.

  • Paul Guilfoyle (Vince)

  • Paul Guilfoyle (Vince)

    Thought that this kooky baby tale couldn’t get more nuts? Cue: Drug laundering miscommunication! In the film, our clueless heroes are awaiting pickup of “a package,” which they naturally assume to be their new bundle of joy. Here, Paul Guilfoyle plays the heroin-handler-cum-unwitting babysitting. A consummate supporting actor, Guilfoyle has appeared in a dozen high-profile films since then, including “Air Force One” and “L.A. Confidential.” From 2000 on, Guilfoyle has starred as Captain Jim Brass in “CSI: Crime Scene Investigation.”

  • Philip Bosco (Det. Sgt. Melkowitz)

  • Philip Bosco (Det. Sgt. Melkowitz)

    Philip Bosco’s career began on the stage; in 1960 he received a Tony Award nomination for his debut in “The Rape of the Belt.” He would appear in three of the biggest movies of the 80’s, “Trading Places,” “The Money Pit” and “Three Men and a Baby,” in which he played a detective sniffing out a drug pickup. Bosco continued his varied career in television and film with such hits as “My Best Friend’s Wedding” and “The First Wives Club.” Most recently, he appeared on the FX series, “Damages.”

  • Margaret Colin (Rebecca)

    Blink and you’ll miss Margaret Colin in the 1987 flick. Here, she plays Selleck’s paramour, watching him care for the baby. Afterwards, she appeared in various television shows, and in 1994 was cast as Jeff Goldblum’s estranged ex-wife in the sci-fi hit, “Independence Day.” Since 2007, Colin has had a reoccurring role on “Gossip Girl,” playing Eleanor Waldorf, mother of Blair Waldorf (Leighton Meester).

  • Cynthia Harris (Mrs. Hathaway)

  • Cynthia Harris (Mrs. Hathaway)

    What’s a quirky comedy without a concerned/maternal neighbor? As Mrs. Hathaway, Cynthia Harris played babysitter for the three men. She is known for her role as Paul Reiser’s overbearing mother-in-law Sylvia Buchman, in the popular 90’s sitcom “Mad About You.” From 2004-2007, Harris appeared in the FX series, “Rescue Me.”

  • Celeste Holm (Mrs. Holden)

  • Celeste Holm (Mrs. Holden)

    Sometimes a son needs his mother, and there’s no better time for a mom to swoop into action than when a child appears on your doorstep. In the film, Celeste Holm played Danson’s on-screen mom, Mrs. Holden. Holm already had quite the storied movie career by the time she signed onto “Three Men and a Baby.” After beginning her career on Broadway, she went on to win the Best Supporting Actor Oscar in 1947 for her performance in “A Gentleman’s Agreement.” Shortly after, the actress realized she preferred theater and opted for plays over feature films. In the 1970s and ’80s, Holm began doing more screen and television acting. In July 2012, the actress passed away at the age of 95.

  • Leonard Nimoy (DIrector)

  • Leonard Nimoy

    Leonard Nimoy was already a respected and accomplished director and actor when he signed onto “Three Men and a Baby.” Best known for playing the vulcan Spock in the original “Star Trek” series (a role he has since reprised on numerous occasions, including the 2009 J.J. Abrams reboot), Nimoy has since done a mix of voice, film and TV work. The last movie he directed was the 1994 crime comedy “Holy Matrimony.”

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